In particular, the 2021 outbreak of Ebola virus disease in Guinea re-emerged from a persistently infected survivor of the previous major outbreak at least five years ago. Some recent Ebola virus disease outbreaks in Africa have been linked to persistent infection in patients who had survived previous outbreaks, according to the paper’s senior author, Xiankun (Kevin) Zeng, Ph.D. Their research, using a nonhuman primate model of Ebola virus infection, appears on the cover of Science Translational Medicine. In a groundbreaking study published on February 9, 2022, scientists describe how Ebola virus, which can persist in certain areas of the body, can re-emerge to cause fatal disease-even long after treatment with monoclonal antibodies. The highly infectious and deadly Ebola virus is shown in this research photo from the National Institute of Allergy and Infectious Diseases.
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